Multiple Conjunctival Metastases As The Initial Sign Of Metastatic Uveal Melanoma
Blumenthal EZ, Garzozi H, Bahir J, Pe’er J.
Am J Ophthalmol. 1997 Oct;124(4):549-50.
Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel.
PURPOSE: To describe a 31-year-old patient who was initially examined with a uveal malignant melanoma metastatic to the ipsilateral conjunctiva.
METHOD: Thirteen months after ruthenium 106 plaque therapy for a ciliochoroidal malignant melanoma, numerous pigmented conjunctival lesions first appeared.
RESULTS: These lesions were excised and found to be metastases of melanoma to the superficial subepithelial conjunctival tissue, composed of epithelioid cells.
CONCLUSION: The appearance of darkly pigmented conjunctival lesions in a patient known to harbor a uveal malignant melanoma, even though lacking any evidence of extrascleral extension or metastatic involvement, may indicate metastatic disease.